Menzies Weekly Seminar - “Melioidosis and molecular public health”


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Presenter:  Prof Bart Currie, Dr Jessica Webb & Audrey Rachlin

Date: Aug 06, 2019

Time: 12:00pm to 1:30pm

Contact person:  Menzies Communications Team
T: 08 8946 8658
E: communications@menzies.edu.au

Location:  Auditorium | John Mathews Building (Bldg 58), Royal Darwin Hospital Campus (also available on WebEx)

Abstract
Melioidosis is a disease of significant public health importance in both humans and animals caused by the environmental bacterium, Burkholderia pseudomallei. Tracing the origin of melioidosis outbreaks and understanding how the bacterium spreads are essential to protecting the health of the public and for reducing mortality through early diagnosis and gold-standard therapy. Each individual case of melioidosis is the result of a single infecting event where the human or animal is exposed to B. pseudomallei in soil and/or water. High-resolution molecular fingerprinting tools have now been successfully used to investigate case clusters and outbreak scenarios in both humans and animals. We recently investigated the aetiology of two fatal clusters of melioidosis in meerkats and hatchling crocodiles on display at a Wildlife Park in Darwin, Northern Territory, Australia using whole-genome sequencing (WGS) and comparative genomic analysis. We continue to demonstrate how useful high-resolution WGS is to enhance epidemiological investigations into transmission modalities and pathogenesis of melioidosis and to better understand the local, regional and global spread of B. pseudomallei.

Biographys
Bart is Director, HOT NORTH; Director, RHDAustralia; Team leader, Tropical and Emerging Infectious Diseases – Read more on our website
Jess graduated from her PhD in 2018 and has begun her postdoctoral career in the melioidosis team working on bacterial pathogenesis and antibiotic resistance
Audrey Rachlin is a PhD candidate based at Menzies, examining the epidemiology of melioidosis in Darwin, Australia and Vientiane, Laos

  • The Menzies seminars are free of charge and open to the general public
  • The presentations will be 20 minutes with 10 minutes for questions.
  • Information about the roster for presentations can be obtained from the communications team on 8946 8658 or communications@menzies.edu.au
  • Please feel free to forward this notice to your colleagues and associates

Menzies Tuesday Seminar Series
Occurs every Tuesday effective Tuesday, June 25, 2019 until Tuesday, December 10, 2019 from 12:00 PM to 1:00 PM, (UTC+09:30) Darwin
12:00 pm | Australia Central Time (Darwin, GMT+09:30) | 1 hr
Meeting number (access code): 571 124 917
Meeting password: utwt8Kwh
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