Menzies Weekly Seminar - “A meta-analysis of the performance of the Carestart™ rapid diagnostic test for the detection of glucose 6 phosphate dehydrogenase deficiency”

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Presenter:  Dr Benedikt Ley

Date: Jul 16, 2019

Time: 12:00pm to 12:30pm

Contact person:  Menzies communications team
T: 8946 8658

Location:  Auditorium | John Mathews Building (Bldg 58), Royal Darwin Hospital Campus (also available on WebEx)

To reduce the risk of drug-induced haemolysis all patients should be tested for glucose-6-phosphate dehydrogenase deficiency (G6PDd) prior to prescribing primaquine (Pq) radical cure for the treatment of vivax malaria. This systematic review and individual patient meta-analysis assessed the utility of a qualitative lateral flow assay from Carestart, USA (CSG) compared to spectrophotometry for diagnosis of G6PDd (PROSPERO: CRD42019110994).

The CSG performed well at the 30% threshold. Its high NPV suggests that the test is suitable to guide Pq treatment, the high LR+ and low LR- render the test suitable to confirm and exclude G6PDd. Further operational studies are needed to confirm the utility of the test in remote endemic settings.

Benedikt is a public health expert with a focus on diagnostics, Malaria and G6PD deficiency. Read More on our website.

Next Tuesday Seminar on July 23:

Jane Nelson - Operational research support manager - Jane has over a decade of experience in good clinical practice working in vaccine trials as a research nurse and later project manager in both Australia and overseas.

    • The Menzies seminars are free of charge and open to the general public
    • The presentations will be 20 minutes with 10 minutes for questions.
    • Information about the roster for presentations can be obtained from the communications team on 8946 8658 or
    • Please feel free to forward this notice to your colleagues and associates

Menzies Tuesday Seminar Series

Occurs every Tuesday effective Tuesday, June 25, 2019 until Tuesday, December 10, 2019 from 12:00 PM to 1:00 PM, (UTC+09:30) Darwin
12:00 pm | Australia Central Time (Darwin, GMT+09:30) | 1 hr
Meeting number (access code): 571 124 917
Meeting password: utwt8Kwh
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