Menzies Weekly Seminar


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Presenter:  Dr. Kamala Ley-Thriemer

Date: Nov 06, 2018

Time: 11:00am to 11:30am

Contact person:  Menzies Communications Unit
T: 8946 8658
E: communications@menzies.edu.au

Location:  Auditorium | John Mathews Building (Bldg 58), Royal Darwin Hospital Campus - available on WebEx

‘Short course primaquine for the radical cure of Plasmodium vivax malaria: a randomized placebo-controlled multicenter trial’
When
Tuesday, 6 November, 11.00­am–11.30am
Where
Auditorium | John Mathews Building (Bldg 58), Royal Darwin Hospital Campus (view map) - available on WebEx

Abstract:
Plasmodium vivax, is a major cause of morbidity and contributor to mortality in Asia, Oceania, the horn of Africa and the Americas characterized by recurrent febrile illnesses weeks to months after the initial infection. These relapses arise from dormant liver stages (hypnozoites) and are the main cause of vivax illness in endemic areas. Primaquine (PQ) is the only widely available drug that kills hypnozoites and therefore preventing relapses, but adherence to the standard 14-day regimen is often poor. Efficacious shorter courses offer an opportunity to increases effectiveness and could therefore be an important tool towards the 2030 elimination goal. The aim of this study was therefore to evaluate the tolerability, safety and efficacy of a 7-day high dose (1 mg/kg/d) PQ regimen in vivax malaria.

Biography:
Kamala Thriemer is a clinical researcher and epidemiologist committed to public health and tropical medicine with more than 10 years field experience in Africa and Asia, coordinating clinical trials to inform treatment of the management of infectious diseases.  Read more on our website.

Next: Tuesday, 13 November 2018

Dr Greg Leach and Dr Jo Wapling | Traditional Australian Medicines Project

  • The Menzies seminars are free of charge and open to the general public
  • The presentations will be 20 minutes with 10 minutes for questions.
  • Information about the roster for presentations can be obtained from the communications team on 8946 8658 or communications@menzies.edu.au
  • Please feel free to forward this notice to your colleagues and associates
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